Mayaro virus (MAYV) Disease: Past, present and future

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Review Article

Author Details : Rajni Yadav*, Megha Jha, Shilpi Prasad, Diksha Jat, Deepak Kumar Jain

Volume : 10, Issue : 1, Year : 2022

Article Page : 7-16

https://doi.org/10.18231/j.jpbs.2022.003

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Abstract

Mayaro virus (MAYV) has haggard increasing interest as an arthropod-borne virus causes eruptions among the human populations of the Western Hemisphere and is transmitted mostly by Hemagogus mosquitoes. MAYV travels in high-density tropical forests or rural areas of Central and South America origin a disease characterized by maculopapular skin rash, high-grade fever and manifest arthralgia that in some patients can continue for extended periods following infection and may be misunderstand as chikungunya. The virus stays alive in sylvatic cycles among mosquitoes and primate reservoirs such as marmosets. Though forest-residence mosquitoes are considered as imperative vectors for MAYV, it has been shown prior to that the virus can contaminate and potentially be transmitted by the mosquitoes, and Although only a little eruptions involving MAYV have been accounted, in the previous years the number of MAYV illness has improved in the northern and central regions of Brazil and many part of world. Disease by MAYV can make mayaro virus disease (MAYVD) which is frequently a clinically identified, sharp, feverish illness connected with extended and painful joint inflammation and swelling. MAYVD may be clinically indistinguishable from chikungunya fever, malaria, dengue, rabies, measles or other arboviral diseases. The full range of disease, routes of infection, virus shedding, sequelae and any rarer means of spread remain undefined. At present, there are no precise marketable tools for the diagnosis of MAYV and utilize of serological methods can be exaggerated by cross-reactivity and the window period. A diagnosis based on clinical and epidemiological data alone is still premature. Therefore, new entomological investigate is necessary and new extremely precise molecular diagnostic methods should be urbanized. This paper presents a systematic and present review of the published MAYV literature ranging from its original report to current eruptions and from the essential virus traits to the clinical and epidemiological traits of this disease.

Keywords: Mayaro virus, Alphavirus, Chikungunya virus, Epidemiology, Mosquito, Arthralgia

How to cite : Yadav R, Jha M, Prasad S, Jat D, Jain D K, Mayaro virus (MAYV) Disease: Past, present and future. J Pharm Biol Sci 2022;10(1):7-16

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