MPharmacological potential of leaf on blood glucose levels, lipid profile, and oxidative stress parameters in diabetic rats

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Original Article

Author Details : Bebyaka Tenone Rosine*, Ntchapda Fidèle, Miaffo David

Volume : 10, Issue : 1, Year : 2022

Article Page : 29-36

https://doi.org/10.18231/j.jpbs.2022.006

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Abstract

Lactuca taraxacifolia is a plant from tropical regions traditionally used in Africa as an anti-diabetic. The aim of the work was to evaluate the antidiabetic and antioxidant potential of the aqueous extract of leaves (AELT) in diabetic rats. To induce diabetes, streptozotocin (55 mg/kg) was injected intraperitoneally into rats. Diabetic animals were divided into groups and treated with vehicle, glibenclamide (10 mg/kg) and AETL (150, 300 and 450 mg/kg). Body weight, blood glucose level, water and food consumption, lipid and oxidative stress parameters were assessed. AELT (450 mg/kg) significantly (p < 0>

Keywords: Lactuca taraxacifolia, lipid profile, Antioxidant Potential, Diabetes, Streptozotocin

How to cite : Rosine B T, Fidèle N, David M, MPharmacological potential of leaf on blood glucose levels, lipid profile, and oxidative stress parameters in diabetic rats. J Pharm Biol Sci 2022;10(1):29-36

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