Alzheimer's disease (AD) presents a complex clinical landscape, notable for progressive mental deterioration and restricted treatment choices. AD exhibits a multifaceted pathology, limiting treatment possibilities, highlighting recent advancements in pharmacological, non-pharmacological, and technological approach. This review discussed the emerging therapies targeting amyloid-β, tau, and neuroinflammation, as well as innovative techniques, such as gene therapy, nanotechnology, and stem cell therapy. This review shows how these novel approaches have the potential to change the treatment of AD and give patients and caregivers new hope. It's a time while AD is better managed and the lives of those impacted are enhanced through the integration of conventional and innovative strategies. This review further discusses the hurdles and potential strategies for transitioning this intervention from research to clinical application.
Keywords: Alzheimer's disease, Novel interventions, Amyloid-β, tau, Neuroinflammation, Gene therapy, Nanotechnology, Stems cell therapy.