Journal of Pharmaceutical and Biological Sciences

Official Publication of Innovative Education and Scientific Research Foundation


Volume 13, Issue 1, Year 2025
Editorial
Tracing the path from nature to pharmaceuticals in drug discovery
Author details: Firoj A. Tamboli
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Review Article
Novel interventions for Alzheimer’s disease
Author details: Snehal Raosaheb Kadam, Shivani Shrikisan Kale, Geeta Keshav Shinde, Chandrashekhar Devidas Upasani, Aman Babanrao Upaganlawar
Alzheimer's disease (AD) presents a complex clinical landscape, notable for progressive mental deterioration and restricted treatment choices. AD exhibits a multifaceted pathology, limiting treatment possibilities, highlighting recent advancements in pharmacological, non-pharmacological, and tec....
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Comprehensive review on methenamine hippurate: Pharmacological activities and role in urinary tract infection prevention
Author details: Chetana P. Bokriya, Tushar A. Dhote, Sachin J Dighade
UTIs are the most common global public health problem, with recurrent UTIs (rUTIs) posing a major challenge due to their impact on quality of life, increased healthcare costs, and the rising trend of antimicrobial resistance. Antibiotic prophylaxis is effective but leads to resistance; thus, new str....
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A systematic review of potential anticancer activities of Muntingia calabura L. With a focus on cellular and molecular mechanisms
Author details: Muna Hamoud Alseaghi, Melati Khalid, Razana Mohd Ali, Muhammad Nazrul Hakim Hakim, Zainul Amiruddin Zakaria
Medicinal plants have been extensively explored for their chemopreventive and antiproliferative properties. Among these, Muntingia calabura has emerged as a promising candidate due to its ability to modulate various signaling pathways involved in cancer progression and suppression. This includes int....
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Nanorobots: The future of precision medicine and targeted therapeutics
Author details: Harsha Varthini Jayaraj, Tamizharasan Sakthivel, Punitha Sundarasamy, Dharanikumar Kesavan
Nanorobots are little devices that can carry out certain cellular and molecular functions. Modern nanorobots, which are based on Feynman's 1959 notion, combine biochips, nano-assemblers, and biohybrid systems to function in biological settings while utilizing either internal or external power so....
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A comprehensive review of cosmetovigilance practices and trends
Author details: Favas, Fathahudheen C, Muhammed Ajnas V.T, Muhammed Safvan E, Muhammed Shibil, Naseef PP
Cosmetovigilance is a critical and well maintained platform to focus on the monitoring, assessing and preventing adverse effects associated with cosmetic products. Now globally the cosmetic industry is expanding so in order to ensure the safety and efficacy of such cosmetic products there should be....
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Emerging paradigms in pharmaceutical care
Author details: Mohammed. Sheeba Kauser, Prasanna Reddy Syamala, M. Pushpalatha, K.R Harshini
Pharmaceutical care has evolved significantly in recent years, transitioning from a product-centered practice to a patient-centered model that emphasizes optimized therapeutic outcomes and enhanced quality of life. Recent trends highlight the integration of digital health technologies, personalized....
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Genetics and therapeutic approaches for sickle cell disease
Author details: Vaibhav Tripath, Adeep Kujur, Rajesh Kumar Nema
Sickle cell disease (SCD) is an inherited blood disorder characterized by hemolytic anemia, vaso-occlusive crises, relentless end-organ injury, and premature death. Currently, red blood cell transfusion and hydroxyurea are the major disease-modifying therapies available for SCD. Hematopoetic stem ce....
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Role of polymers in enhancing the performance of floating drug delivery systems
Author details: Digvijaysinh Ramesh Kale, Kiran Kashinath Shinde, Darshan V. Shah
The Floating Drug Delivery System (FDDS) is a specialized dosage form designed to remain buoyant in the gastric environment, thereby enhancing drug absorption and bioavailability, particularly for drugs with a narrow therapeutic window or poor solubility. Polymers play a central role in enha....
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Original Article
Neuroprotective effects of Akebia Quinata extract on cognitive impairment in rat models
Author details: Namrata M. Waghmare, Vinay V. Sarode, Pragati G. Zalwade, Dhamsheela N. Gondane, Aditi B. Daiwalkar, Bhushan R. Gandhare
Background and Aim: Alzheimer’s disease (AD) involves cognitive decline driven by cholinergic dysfunction, oxidative stress, and neuroinflammation. This study investigates the neuroprotective efficacy of Akebia quinata ethanolic extract (AQE) against scopolamine-induced Alzheimer's Disease (AD)....
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